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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b4d18f6028e1bf0e2b2e6b7cb9570d459b50d048715a94e02cde44e652c7ddf' 
  AND token = 'M4rW016E6YSDMel0Uob4v8u83C5wenGgRL88EyTL1Lc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}