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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b49623b8e5753f546870d412cae924a5114af51f87a765f4e388af9729f553e' 
  AND token = 'bM6FsK37dFJ6B7U4qWJHK5YR9gxc9GHriC9DeZCCAYY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}