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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49265d8a9c20ce34e20988648b41f2fbed45f6979d5dae6600c53aa44d4e72f1' 
  AND token = 'shK6cOwryeK3zyiajX6udROzOvfm0rfejyaunJDF4IM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}