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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b956d27393b64f2ed5216105ed40eeeb03878a3cffbbcaadda249c22f7314d81' 
  AND token = 'WWGSB0I/7lzpX1IseAiTNUapAoannsY9VYjuM1bgnDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}