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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48af6e3cbb955b18ed71abee287d623d6d718413803d1a249926b07e2bda9018' 
  AND token = 'nrqz3k8+C1xmeZr551NJMxpSzDH7pVgXV7CD2NFmWEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}