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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52a04e90d4271ee460334ea42ef6ea06719f42b21d64ef29e8b5bce5b4eaecac' 
  AND token = 'FrQeuAD8DJSmDunmHen4o3tcTwV/AaHpYIRwtfB+LZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}