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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '487b8bdb68a432476c06ab9db551fb2bc199519e8ac74e05c857361b53c89399' 
  AND token = 'f4n0+eb8SPpTvUsGRHSbtr3GaQ7PzsVHWf216xKR4B8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}