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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc11ae6ff803bfbc394345a8f57466d9c4821e73b3a7a90dda6b968bd2113b86' 
  AND token = 'axQeEM/VBeQdsQx8cOUqs8NrLkEjVXyWfoIy4D5RlAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}