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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50d7ceaf52be5406e528d7259b239ddab1717b62b5cc20dad4c64c3e5db4b46f' 
  AND token = '0JxB9IlM7WaB9iFXWdvhwOgFgEZL6RO8bJyuinpgFNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}