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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ac8687d3c25d3dc341d04516918233b5716b74e59b0a384e75192cc945b55c0' 
  AND token = '2cYf25atWJdA23O0DN/lISMV9z1Qvm1ozZxIt9jLViQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}