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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43c832235524572efabf8dc6026b09cd6b5fd404897c36a2471c5e88e1557e2f' 
  AND token = 'r/QkIbZV1dlBV+zHPhAGA4PEtWt5XeneoNOw96s6gs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}