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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4256c2ff481206a1cecae91a3f2c13dc329ffd8e31be5e740780f365bc8424c' 
  AND token = 'YMKyzU62Qh0nTf0Ezt67t8IOoD6Wdr1hTS17skrA/AU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}