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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7145557f6dbe1ca2fec05fdaf6f0cd64a1ef833387e39ab0e4ebe6fc5698e411' 
  AND token = 'Nu3D86oXU6duV5QdkxM5zKiZgYuo+rI4ZoDFnysB/F0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}