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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '800e3891d06cc85764f6c280f584d7014c4f851c82ef7d58056b934a70187a6f' 
  AND token = 'z2dEoGSNiRv7jOBghGeVyryhrOiqLdqHrdvy/D3hXmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}