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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd22cdeb58e486f7df719cddecb50de4971d61abd32e7363c667f11bce28bcd01' 
  AND token = '4a3MpXYQobJSW1r5OKek24N/v4yiuKrhP0XUHxrspUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}