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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8347eccc3f721099c102ea5b07646cc4476393c4b7535e7a3e4b73588a88134' 
  AND token = 'pPWGkcf9B8M9hUjkOcqE1lHpHcLPO5zk4DyoPZSAY1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}