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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a92fc516babe1f7696ae6f3d3a8a9be9df173f67017d32279d1bffc79ea2226' 
  AND token = 'FtZnC07oduzxFMeXx3KBiHwViagiVCDjoKrA6+nNJCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}