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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2901307e8e50c99ef7d1fb73022dfac8a2e7fedf9d18701a450ff483b2e98745' 
  AND token = '8uHjuSFCcB5bKZJYawf6c/KbevnhxZ6zxdtOModeetc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}