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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9733f25ca04d4ff46f81fc7af297b54bebef79966ea814e4bf9f327eabee3074' 
  AND token = 'P8ZmmjQdt8pjx2QDBWIHmGlyHHrtXFuSaMzbQswpaGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}