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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e39e80d34289423e9751eb79fd405b4de6762725717121bca4e15c21d7f0949' 
  AND token = 'b9ePI5ChL0wR/iMRFWrMd2AbZnhifeozA3KYSPxVswo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}