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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'defd34d84720ca1e95906c191346d1fee978b7b1f91405363af753aad4394f94' 
  AND token = 'TlegIg5xh2acZFPdahJYy3Gp3AJEufh3IhpGRb0YDhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}