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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f2356949da43607c27f31ddb50b856354b49925a399a112df1eeae9e3f3c66c' 
  AND token = 'r8SVdRRRqRn8x8sGoMFCkUxkPpTtfMtdYurB3JWgyEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}