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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '392af0a3ffec7477dcec7e6fe253465d728c7cd2673df2d6b1da3ceae4d9e756' 
  AND token = 'vgYiLhHkfYC2Vjngqm1zmQ6LhS0yffujVZ9G0DCpSDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}