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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '191e78e7c3c9434b793b825de2a9a229e24f5823f991b07f494ccbde63391946' 
  AND token = 'ClH/GjVC7cxVjXPoN148A3go37jlLsPBEASliuS7EXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}