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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2790b6c99d205f751065cd7fccd57243ad8c3d24dc57a45c8eac7cdec9e0e249' 
  AND token = 'xtr1iiFKDoncL00RGz6R11e8qI7KoIBOJXCAJaGr+8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}