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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dff43434c2098c64cd3464fea01289ad0acc8a617121f67830f24c5cc2cd285' 
  AND token = 'vyyxkTH8aUXEtvM4aFlWix245ZTPdRdcCBZ8xufJY6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}