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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f0eeeed953eb1431464f60d2d2e51e3463e149dea8e13e97c84f3ba347e9255' 
  AND token = 'DThYnqFOUhjDlKY4YxXSNvYYXfiaxfaAHw/Hl9EkEQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}