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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca3c6c1362a59d24d2bb7e904f00c479281561977eca35539f766c0820e86d7c' 
  AND token = 'wXFVWetevB3vEHV2b2N91RfnWQ0HTzpymHEr6/cOB9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}