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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ced87aaa28f7745f1669d606a68fc9da2506b1abad5fcc77b2ebfd492144a55' 
  AND token = 'F5c7zIL07wU5p/GiO9N1cEyLF82ktfqOd+iZ8kQzeL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}