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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70621c535e3d82633360b8e27b891e27a2ea6d396303a42baff5d171656bb703' 
  AND token = 'c/R+YT5Mir+8CkE+7yaMp+ckieETR+s9xpO6Ks4wzBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}