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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '685a03fe06a9306f607e59cd3931d4173c0a100afaf34e8d638e0c1ef9cd3ec0' 
  AND token = '8wmFBa9pBVAVxiRgAd29+qQZh3Jt1VxNJqtTZ2Gxf7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}