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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2a620c5dd2876656b6e8ce65a52fe2eab79ca21ca79b39f107e44c551c36fdd' 
  AND token = 'bZq1Isb0p9VcaDj027y2sF0a/GaHsIJcKlo4Viu53is=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}