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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a653fa1f3d3aeb6b654c5ed10c85d2c88d0ebfca8687e9372ce9705c636d0184' 
  AND token = 'd5NbDmzQDFq9ocPkpb8+gQ/BQM69n+HGfm+o8aQPEJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}