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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be6ab49a0b47ac89f123f7b0da6502b2c2e2e94685eeba8d43bcd84db4967130' 
  AND token = 'r9M781Gp6Tc86nnOAfVmzvDyKLTglgj8/TnGTJd6gYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}