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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb868ff869e2f4b325556872aefba0bfd9b2bdd37d430d1ef3fd0449abb5f4c5' 
  AND token = 'xawzKDmIDbuo3XCDXj7y0c43JU7H9MxHiMFMAqpfMGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}