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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41ccc060b7692f61921e21bf4099f7c13250a05ef12b7e1f5f73b1193c67246d' 
  AND token = 'qdRSmSplhgdXKc1Ri5XrqfD1Ag9s/Fxju+hSTff0dHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}