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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b6310f17e13714e90107c0025f38308ba34c072f04ced83b9851c31b263a768' 
  AND token = 'EcIIAcgnbY+Z52o6VnxotkND2dNvNULyUmaKXZNuhj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}