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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3831995500ecd365c684d8442dbeb8fb9e7e54e009f23e6153ce9ac0171a2668' 
  AND token = 'txbSj5jEcwXPmmm6MxPJ9EEy5/wmKFhAYp5W9Xl2KcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}