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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e209c30228a7832edb18bb4d3d68434d1bfecc70d7005c5820595f9216d67e11' 
  AND token = '8/zz6lLRc3F8o61/lKcoUiPlBWS1iBZvSWSKHeMGnwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}