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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfe13709af0ba3b28b4fa04ce9d5b74e54192fa1e6e16194121bb10a0a9d0c22' 
  AND token = 'ugWOPznwaw+ERmhKE0A/a2+2VesaRQz7QJJ3EsXLYUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}