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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '205e4e7875cda3a1bdd28a793ce08bc9a6829c7e9157cb6b8335d4f35efd45ca' 
  AND token = 'IhRV7Ep8b+lqeGS6pgybKaG2mm/Ii2oXI+ydAoC1pAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}