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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9550f1d65b80e203d0d59f71a21997daf9282f4401dfb55116f4a3b970d0c4fc' 
  AND token = 'SDJkB8ckcAc9UzkftIYLNkPoxxRmn3ZcvD9XXGfVfHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}