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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fad19a1e86ed15345b7c4267247fa2782bdeabcc0912719eecc134d0a5920a49' 
  AND token = 'z1fZfP+1WiP3D8m9vRayaBdW0SoVL3/0WI8sNvGyLtk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}