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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1052a1b54f18497b9349516eaea27648308115f351a4f40322c3502ca750d01' 
  AND token = 'qgLE46PM7K93FWsT5Bnme1KHN59WSx42wHigDya9jJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}