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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b28281941512644a2f7a6b29591176fb4f8b0e4130492a3e065f02594071979d' 
  AND token = 'W9B6zSSnfy5He6C3HJkOaiNUVoSgVkB4/LHln2R/Wfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}