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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5ed12f6f3015e958c2d303332c3616211dc1980b0611e290e4bd7007fe79b3f' 
  AND token = 'qwlSTEQtiqpw5XxtV3blR+VDnr+MnbFdJE/17awiT/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}