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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49d07529e0a0010b26120e75105f604e4ed77d84b722781843aef95ed1f32692' 
  AND token = 'IHklPb397e8Gof9cNYyRqbDvQZ4v/QNX18T3pollY6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}