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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d9765fa4f31bc668844b84b3f0e9cb592a42f129099baa33e93caf6b12da43f' 
  AND token = 'MvIVO8Ox5DTp3agSB0DQi8TtO9emOrTVUJbm+H28UUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}