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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '337eff97bf997943e026cfa1a9169faeabf1b316ad2cdb5f480f07e8d62e35ca' 
  AND token = 'KkRr5IUqJaGq2Y+R2CSZJYSG37LdkadVvQ75dRsBnIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}