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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5466b9d9487dba5536d6e913ce99af030bec1eb2de90fd18663836098b76aec1' 
  AND token = 'c3SpbROqqUfGK0kAx5Ein7p/YN2YpmtbGGpBuJ2yYCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}